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ПАНКРЕАТИЧЕСКИЕ ЗВЕЗДЧАТЫЕ КЛЕТКИ: СТРУКТУРА И ФУНКЦИЯ. ЧАСТЬ 1. МОРФОФУНКЦИОНАЛЬНАЯ ХАРАКТЕРИСТИКА ПАНКРЕАТИЧЕСКИХ ЗВЕЗДЧАТЫХ КЛЕТОК В ФИЗИОЛОГИЧЕСКИХ УСЛОВИЯХ

  • Л. А. Можейко УО «Гродненский государственный медицинский университет»
Ключевые слова: покоящиеся звездчатые клетки, поджелудочная железа

Аннотация


Цель обзора – на основе научных литературных сведений дать современную морфофункциональную характеристику звездчатых клеток здоровой поджелудочной железы.
Установлено, что в физиологическом состоянии звездчатые клетки поджелудочной железы составляют небольшое количество по сравнению с другими панкреатическими клетками (4-7%). Они присутствуют в периацинарном пространстве, охватывая длинными цитоплазматическими отростками основание ацинуса, а также встречаются около выводных протоков и кровеносных сосудов. Специфическим признаком панкреатических звездчатых клеток является экспрессия глиального фибриллярного кислого белка. Покоящиеся звездчатые клетки характеризуются наличием витамин А-депонирующих липидных капель. Они выполняют существенную роль в поддержании нормальной структуры органа, регулируя синтез и разрушение белков внеклеточного матрикса. Предполагаются также другие функции панкреатических звездчатых клеток, такие как прогениторная, иммунная и медиаторная.

Литература


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Опубликован
2019-02-12
Как цитировать
1.
Можейко ЛА. ПАНКРЕАТИЧЕСКИЕ ЗВЕЗДЧАТЫЕ КЛЕТКИ: СТРУКТУРА И ФУНКЦИЯ. ЧАСТЬ 1. МОРФОФУНКЦИОНАЛЬНАЯ ХАРАКТЕРИСТИКА ПАНКРЕАТИЧЕСКИХ ЗВЕЗДЧАТЫХ КЛЕТОК В ФИЗИОЛОГИЧЕСКИХ УСЛОВИЯХ. journalHandG [Интернет]. 12 февраль 2019 г. [цитируется по 22 декабрь 2024 г.];2(1):21-5. доступно на: http://hepatogastro.grsmu.by/index.php/journalHandG/article/view/58
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