HЕLICOBACTER PYLORI INFECTION AND CHRONIC GASTRITIS AMONG SOLDIERS OF SERVICE FOR A FIXED PERIOD
Abstract
Background. Helicobacter pylori infection and chronic gastritis are considered as an important problem in the context of progression with the development of severe forms of pathology.
Objective – to еvaluate the conjugation of endoscopic and morphological data of the gastric mucosa in dyspepsia in the absence of erosive and ulcerative lesions in conscripts.
Materials and methods. 165 men aged 18-26 years from the number of regular servicemen from one of the garrisons of the military units of the Air Force and the air defense forces of the Armed Forces of the Republic of Belarus with symptoms of dyspepsia, who underwent an endoscopic examination of the upper gastrointestinal tract and a morphological study of the biopsy specimens of the stomach mucosa.
Results. Hеlicobacter pylori infection was detected in 61.2% (95% CI 53.6-68.3%) of patients; the frequency of the stomach corpus contamination was 37.0% (95% CI 29.9-44.6%), antrum – 60.0% (95% CI 52.4-67.2%), both divisions – 35.8% (95% CI 28.8-43.3%). Chronic gastritis occurred in 154 patients, of whom 103 (66.9%; 95% CI 59.1-73.8%) had antral gastritis and 51 (33.1%; 95% CI 26.2-40.9%) – pangastritis. In case of gastritis with atrophy (excluding the gastric department for localization of atrophy and Hеlicobacter pylori contamination), the frequency of infection (40.6%, 95% CI 25.5-57.7%) was lower in comparison with the group without atrophy (66.2%; 95% CI 57.8-73.7%; χ²=7.09, p=0.01). Conclusion. Among military men of urgent military service (men 18-26 years old) with symptoms of dyspepsia in the absence of erosive ulcers of the upper part of the gastrointestinal tract, there is a high incidence of Hеlicobacter pylori infection (61.2%; 95% CI 53.6-68.3%) and chronic gastritis (93.3%; 95% CI 88.5-96.3%).
References
1. Bova AA, Kriushev PV. Dispepsija v svete Rimskogo III Konsensusa. Voennaja medicina. 2009;3(12):15-24. (Russian).
2. Sugano K, Tack J, Kuipers EJ, Graham DY, El-Omar EM, Miura S, Haruma K, Asaka M, Uemura N, Malfertheiner P; faculty members of Kyoto Global Consensus Conference. Kyoto global consensus report on Helicobacter pylori gastritis. Gut. 2015;64(9):1353-1367. doi: 10.1136/gutjnl-2015-309252.
3. Makarenko EV. Infekcija Helicobacter pylori v gastrojenterologii. Vitebsk: VGMU; 2009. 238 p. (Russian).
4. Marakhovskiy KYu. Sopostavlenie u vzroslyh i detej sostojanija slizistoj zheludka, kolonizirovannoj mikrobom Helicobacter pylori [Comparison in the adult and children of the state of the gastric mucosa, colonized with Helicobacter pylori]. In: Belorusskaja medicinskaja akademija poslediplomnogo obrazovanija, executive editor. Almanah Gastrojenterologija. Sbornik recenzirovannyh statej i tezisov [The almanac. Gastroenterology: The collection of reviewed articles and theses]; 2004 fevralja 25-26; Minsk, Belarus. Minsk: DoktorDizajn; 2004. p. 88-96. (Russian).
5. Marahovskij KJu. Soprjazhennost izmenenij slizistoj zheludka, associirovannoj c Helicobacter pylori, u detej i vzroslyh v urbanizirovannoj populjacii. Medicinskie novosti. 2004;9:17-23. (Russian).
6. Pimanau S, Makarenka A, Voropaeva A. Prevalence young adult population and patients with duodenal ulcer: study in Belarus. Helicobacter. 2004;9(5):1969-1973.
7. Makarenko EV, Pimanov SI, Voropaeva AV, Bondarenko VM. Rasprostranennost infekcii Helicobacter pylori v Vitebskom regione. Vestnik Vitebskogo gosudarstvennogo medicinskogo universiteta [Vestnik of Vitebsk state medical university]. 2005;4(4):12-19. (Russian).
8. Rudoj AS, Gorustovich AG, Burak AJu. Vlijanie fenotipicheskih harakteristik nedifferencirovannoj displazii soedinitelnoj tkani na osobennosti morfologicheskoj kartiny hronicheskogo H. pylori- associirovannogo gastrita v sopostavlenii sadaptacionnym potencialom kardiorespiratornoj sistemy. In: Sikorskij AV; Kulaga OK; Stahejko AV; Terehova TV, editors. Innovacii v medicine i farmacii 2012. Materialy nauchno-prakticheskoj konferencii molodyh uchenyh; 2012 Oktjabrja 23; Minsk, Belarus. Minsk: BGMU; 2012. p. 68-75. (Russian).
9. Papko SB, Kleckij SK, Silivonchik NN. Jeritematoznaja gastropatija u podrostkov = gastrit? [Erythematous gastropathy in adolescents = gastritis?]. In: Belorusskaja medicinskaja akademija poslediplomnogo obrazovanija, executive editor. Almanah Gastrojenterologija. Sbornik recenzirovannyh statej i tezisov [The almanac. Gastroenterology: The collection of reviewed articles and theses]; 2004 fevralja 25-26; Minsk, Belarus. Minsk: DoktorDizajn; 2004. p. 119-123. (Russian).
10. Talley NJ, Stanghellini V, Heading RC, Koch KL, Malagelada JR, Tytgat GN. Functional gastroduodenal disorders. Gut. 1999;45(Suppl 2):II37-42.
11. Rugge M, Kim JG, Mahachai V, Miehlke S, Pennelli G, Russo VM, Perng CL, Chang FY, Tandon RK, Singal DK, Sung JJ, Valenzuela JE, Realdi G, Dore MP, Graham DY. OLGA gastritis staging in young adults and country – specific gastric cancer risk. Int. J. Surg. Pathol. 2008;16(2):150-154. doi: 10.1177/1066896907307238.
12. Waye JD, Mařatka Z, Armengol Miró JR. Digestive endoscopy: terminology with definitions and classifications of diagnosis and therapy. Bad Homburg: NORMED Verl; 2011. 222 p.
13. Aruin LI, Kapuller LL, Isakov VA. Morfologicheskaja diagnostika boleznej zheludka i kishechnika. Moscow: Triada-X; 1998. 496 p. (Russian).
14. Dixon MF, Genta RM, Yardley JH, Correa P. Classification and grading of gastritis. The updated Sydney System. International Workshop on the Histopathology of Gastritis; 1994 Houston. Am. J. Surg. Pathol. 1996;20(10):1161-1181.
15. Capelle LG, de Vries AC, Haringsma J, Ter Borg F, de Vries RA, Bruno MJ, van Dekken H, Meijer J, van Grieken NC, Kuipers EJ. The staging of gastritis with the OLGA system by using intestinal metaplasia as an accurate alternative for atrophic gastritis. Gastrointest. Endosc. 2010;71(7):1150-1158. doi: 10.1016/j.gie.2009.
1.png)
