CHARACTERISTICS OF ALVEOCOCCOSIS OF LIVER AND OTHER ORGANS
Abstract
Background. Alveococcosis is caused by helminth Echinococcus multilocularis and is characterized by infiltrative growth of parasitic tissue, metastasis, late diagnosis and high mortality.
Objective. To present pathomorphological changes in the liver, lungs, brain and the results of diagnostics and treatment for alveococcosis.
Material and methods. Clinical manifestations, morphological changes, tactics and results of surgical treatment of 5 patients suffering from liver alveococcosis with simultaneous lesions of the lungs and brain were analyzed.
Results. In all cases, alveococcosis was asymptomatic or oligosymptomatic. The final diagnosis was established only during surgical interventions. Despite the large size of lesions in the liver, all patients underwent radical or conditionally radical surgical interventions, as well as resection of identified foci in the lungs. The postoperative period was without any peculiarities and 1.5-3 weeks after the intervention the patients were discharged in satisfactory condition. Relapse of the disease in the liver was not noted. However, in one patient suffering from concomitant alveococcosis of the liver and brain after advanced liver resection, the inflammatory process in the brain, despite prolonged etiotropic treatment, progressed, was complicated by hydrocephalus, secondary purulent meningitis, and death after 4 years.
Conclusion. Monitoring patients who successfully underwent operative intervention for alveococcosis should be performed for life because of possible recurrence or metastatic injury of other organs.
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