МИТОХОНДРИАЛЬНАЯ ДИСФУНКЦИЯ – КЛЮЧЕВОЕ ЗВЕНО В ПАТОГЕНЕЗЕ ПАТОЛОГИИ ПЕЧЕНИ ЧЕЛОВЕКА (ВТОРАЯ ЧАСТЬ)
Аннотация
В первой части статьи авторы акцентировали внимание на биоэнергетической роли митохондрий и некоторых причинах, вызывающих их дисфункцию. Во второй части обзора представлены последние достижения в функционировании мест контакта митохондрий с некоторыми мембранными органеллами, что подтверждает растущую важность изучения участков межорганельного физического контакта митохондрий в регуляции клеточного гомеостаза. Хотя конкретные механизмы всех коммуникаций остаются еще неясными, расшифровка связей в сетях органелл имеет решающее значение для понимания того, как строятся биологические системы и почему они могут разрушаться.
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